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Ivabradine: Uses, Side Effects, Contraindications, Drug Interactions

Last reviewed by Drug Expert on June 13th, 2019.

What Is Ivabradine?

Sold under the brand name Corlanor, Ivabradine is a prescription medication that can lower heart rate and decrease heart failure symptoms. Physicians usually turn to Ivabradine in patients whose heart conditions cannot be managed with beta blockers. It is available in 5mg and 7.5mg tablets. The usual adult dosage is 5mg twice daily, but may be adjusted due to the patient’s particular circumstances. It is important to take Ivabradine exactly as directed, as it can alter your heart rhythm. It is best taken with meals for proper absorption.


What Is Ivabradine Used For?

Ivabradine is most often used in patients with heart failure, to reduce symptoms and slow progression of the disease. It may also be used in patients with certain heart rhythm disorders including supraventricular tachycardia and atrial fibrillation. Recently, physicians have started to use Ivabradine in patients who suffer with tachycardia related to dysautonomia.

Possible Ivabradine Side Effects:

Consult with your doctor immediately if any of the following side effects occur.

  • Bradycardia (slow heartbeat)
  • High blood pressure
  • Blurred vision
  • Chest pain
  • Dizziness
  • Fainting
  • Irregular heartbeat
  • Fast heartbeat
  • Headache
  • Pounding in the ears
  • Shortness of breath
  • Lightheadedness
  • Extreme fatigue
  • Confusion

heart failure medication


Before taking Ivabradine, consult with your physician if you have any of the following conditions. Ivabradine can produce adverse effects or worsening of any of the following conditions:

  • Bradycardia
  • Dysautonomia
  • Chiari Malformation
  • Acute Decompensated Heart Failure
  • Liver disease
  • Renal impairment
  • Hypotension

It is also important to consult with your doctor if you have a pacemaker or if you are currently pregnant or breastfeeding before you begin taking Ivabradine.

dysautonomia meds

Possible Drug Interactions

Taking Ivabradine with any of the following medications can produce adverse effects. Always check with your physician before taking Ivabradine with any of the following:

  • Clarithromycin
  • Digoxin
  • Metoprolol Tartrate
  • Metoprolol Succinate
  • Ranolazine
  • Ventolin
  • Verapamil
  • Zofran
  • Zoloft

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