Contents
- What is Metadate? What is Adderall?
- Are Metadate and Adderall the same thing?
- How does Metadate work? How does Adderall work?
- Metadate and Adderall Uses
- Metadate and Adderall available dosages and forms
- Metadate side effects
- Adderall side effects
- Can you buy Metadate and Adderall over the counter?
- Metadate and Adderall price
- Who should not take Metadate or Adderall?
- How should Metadate and Adderall be used?
- How many times and how often can patients take Metadate and Adderall?
- What if I overdose Metadate and Adderall?
- What if I missed the dose of Metadate and Adderall?
- Can I drink alcohol while taking Metadate and Adderall?
What is Metadate? What is Adderall? |
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Metadate, or Metadate CD, is a Brand name for a central nervous system stimulant drug that contains methylphenidate as an active ingredient. Methylphenidate affects chemicals in the brain and nerves that contribute to impulse control and hyperactivity.
Adderall is a Brand name for a central nervous system stimulant preparation that contains the combination of amphetamine and dextroapmhetamine. Amphetamine and dextroapmhetamine affects chemicals in the brain and nerves that contribute to impulse control and hyperactivity. |
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Are Metadate and Adderall the same thing? |
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Metadate and Adderall have many similarities but they are not the same thing. Both drugs are CNS stimulants. They work by speeding up the electrical and chemical transmission throughout the central nervous system. They do this by increasing the brain activity of dopamine and norepinephrine which are linked with the development of ADHD.
Both are available as short-acting and long-acting formulations and both can be addictive and have a high potential for abuse. However, these two medicines have some differences. Their active ingredients are chemically different. Metadate contains methylphenidate as an active ingredient while Adderall contains combination of four different amphetamine salts. Like Metadate, Adderall keeps dopamine and norepinephrine working in the brain. However, Adderall does something that Metadate doesn’t. It makes the cells pump out more of the neurotransmitters. Another difference is their activity time. Adderall is active for 4-6 hours while Metadate is only active for 2-3 hours. But, this doesn’t mean that Adderall is more useful. Many patients prefer the shorter-acting Metadate as they can better control the timing of side effects, such as sleeplessness and loss of appetite. Studies found that there are no conclusive evidences that any of drugs used for ADHD treatment, including either Adderall or Metadate, works better than the other. The general recommendation is that if one of drug is not as effective because of side effects or effectiveness, the other should be tried. In general, there are some minor differences between the two. |
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How does Metadate work? How does Adderall work? |
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Amphetamine and dextroamphetamine as non-catechloamine sypathomimetic substances are used in combination for the treatment of narcolepsy and attention-deficit hyperactivity disorder (ADHD). Adderall contains equivalent amounts of amphetamine aspartate, amphetamine sulfate, dextroamphetamine sulfate and dextroamphetamine saccharate. Amphetamines stimulate norepinephrine release from central adrenergic receptors.
At higher doses, amphetamines may cause dopamine release from the nigrostriatal dopamine systems and the mesocorticolimbic system. Amphetamine can also work as a direct agonist on 5-HT receptors in CNS and may inhibit enzyme monoamine oxidase. Peripherally, it is suggested that amphetamines cause noradrenaline release by acting on the nerve terminals of adrenergic alpha- and beta-receptors. Serotonergic pathways modulation may contribute to the calming effects. Interaction with VMAT enzymes enhances release of dopamine and 5-HT from vesicles. It may also directly cause the reversal of DAT and SERT. Methylphenidate mechanisms of action appear to be similar to dextroamphetamine’s. As a CNS stimulant Methylphenidate is used most commonly for the treatment of ADHD in children and for narcolepsy disorders. Methylphenidate acts by blocking the dopamine uptake of adrenergic neurons in CNS by blocking transport of dopamine or carrier proteins. Methylphenidate has its actions on the cerebral cortex and the brain stem arousal system, and causes increased sympathomimetic activity in the CNS. This drug may also alter serotonergic pathways as a result of changes in dopamine transport. |
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Metadate and Adderall Uses |
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Metadate indications are: Attention Deficit Hyperactivity Disorder (ADHD), narcolepsy and depression.
Addrall indications are: Attention Deficit Hyperactivity Disorder (ADHD) in children older than 3 years of age and narcolepsy. |
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Metadate and Adderall available dosages and forms |
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Metadate side effects |
Adderall side effects |
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Can you buy Metadate and Adderall over the counter? |
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No, Metadate and Adderall are available only as prescription products. | |
Metadate and Adderall price |
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Who should not take Metadate or Adderall? |
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How should Metadate and Adderall be used? |
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How many times and how often can patients take Metadate and Adderall? |
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Adult Dose of Adderall for Narcolepsy:
Pediatric (6 years to 12 years) Dose of Adderall for Narcolepsy:
Pediatric (older than 12 years) Dose of Adderall for Narcolepsy:
Adult Dose of Adderall for ADHD:
Pediatric (6-12 years) Dose of Adderall for ADHD:
Maximum Dose: 30 mg once daily upon awakening. Pediatric (13-17 years) Dose of Adderall for ADHD:
Metadate dosage for ADHD and narcolepsy:
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What if I overdose Metadate and Adderall? |
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What if I missed the dose of Metadate and Adderall? |
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Can I drink alcohol while taking Metadate and Adderall? |
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Patients should avoid drinking alcohol while there are on Metadate or Adderall treatment. Metadate and Adderall are stimulant drugs, and alcohol is a depressant. Administrating two drugs with opposite effects may confuse the body, and this can be partly responsible for the unpredictable outcome.
It also makes a problem with how the body metabolizes and procceses the drugs. Effectiveness of Metadate or Adderall can be compromised in order to deal with the other. Stimulant drugs can mask the psychological effects of alcohol. Patient may not feel the alcohol effects, and may ingest more than normal amount, possibly drinking to a dangerous state. When stimulant effects stopped, the person still has all amounts of the alcohol left in the bloodstream. This has the ability to make someone who moments before felt fine, feel instantly drunk, and possibly past a state they can manage. When doctors prescribes Metadate or Adderall for adult patients, they will ceratinly ask them if they have any history of alcohol or drug dependency. Metadate and Adderall can create dependency issues, and for those with dependency history it may be dangerous to attempt this treatment. Because alcohol effects can be minimized with these drugs, it is not recommended to start with Metadate or Adderall tratment for patients on alcohol dependancy recovery or in those who may have an increased chance of developing an alcohol dependency during the treatment. |